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Revatio

Revatio is a brand name of a synthetically produced agent called Sildenafil. It was discovered in the early 2000s as a medicine for the treatment of erectile disorders in men. Clinical trials proved its safety and efficiency, and the drug was launched into the market under the name of Viagra. Its principle of action is similar to all existing medicines relating to the family of PDE-5 inhibitors. Sildenafil speeds up the blood flow in the pelvic area by making vessels relaxed, thus providing a better penile blood supply and causing a firmer erection. Later on it was discovered that Viagra can be also used for relieving symptoms of benign prostatic hyperplasia. It stimulates fluid circulation providing its efflux from the prostate gland.

Other names for this medication:
Caverta, Intagra, Kamagra, Penegra, Revatio, Silagra, Sildenafil, Sildenafila, Sildenafilo, Sildenafilum, Sildigra, Suhagra, Veega, Zenegra

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Also known as: Sildenafil

Description

Revatio is approved to treat erectile dysfunction (ED) in men. With ED, you have trouble getting and keeping an erection that’s firm enough to allow you to have sex.

What causes an erection?

When you’re sexually aroused, either through sexual thoughts or touch, your brain sends messages to your penis. These messages cause certain chemicals to be released in your penis.

One of these chemicals, called cyclic GMP, relaxes and widens certain blood vessels in your penis. Cyclic GMP also relaxes the muscles around the erectile tissue in your penis that’s called the corpus cavernosum. These actions allow blood to flow into the corpus cavernosum, which causes your penis to get hard and become erect.

What happens with ED?

ED can occur if you have certain problems that affect your body’s ability to have an erection. The condition can result from problems with messages being sent from your brain. ED can also result from problems with blood flow into your penis.

What does Revatio do for ED?

Revatio works to treat ED by helping you have and maintain an erection. The drug does this by improving blood flow into your penis when you’re sexually aroused.

Revatio is a type of drug called a phosphodiesterase type 5 (PDE5) inhibitor. It works by inhibiting (blocking) the action of an enzyme called PDE5. (An enzyme is a protein that helps chemical reactions to happen inside your body.)

Normally, an erection goes away when PDE5 breaks down the cyclic GMP in your penis. But Revatio blocks the action of PDE5, so it allows cyclic GMP to keep working for a longer period of time than usual. This action improves blood flow to your penis and helps you to have and keep an erection.

Does Revatio increase a man’s sex drive?

No, Revatio doesn’t directly increase your sex drive. And it doesn’t make you sexually aroused. However, some men find that if Revatio works to treat their erectile problem, it also increases their sexual confidence. And this may lead to an increased sex drive.

How can I tell if Revatio’s not working?

Revatio may not work for everyone, and it may not work every time you take it.

If you’re sexually aroused, Revatio should work to help you have or keep an erection within 30 minutes to 2 hours. But if you don’t get an erection within 4 hours after taking a dose, Revatio didn’t work for you this time.

If the drug doesn’t work for you, you shouldn’t take another dose until at least 24 hours later. And talk with your doctor if you feel Revatio isn’t helping to treat your ED. They may recommend that you try a different medication for your ED.

How can I get Revatio to work?

It’s important to remember that Revatio only works if you’re already sexually aroused. Arousal may involve having sexual thoughts, looking at sexual images, masturbating, or engaging in foreplay.

But if you feel anxious, nervous, depressed, or stressed, your body may not respond well to sexual stimulation. If this is the case, try to relax, make yourself comfortable, and take your time. In addition, it’s best to avoid drinking a lot of alcohol. This is because consuming large amounts of alcohol can make it more difficult for you to get an erection.

If you’re having trouble getting an erection, even while using Revatio, talk with your doctor.

Is Revatio a blood thinner?

No, Revatio isn’t a blood thinner. Instead, it belongs to a class of drugs called phosphodiesterase type 5 (PDE5) inhibitors. (A class of drugs describes a group of medications that work in a similar way.) Revatio works by inhibiting (blocking) the action of a certain enzyme in your body.

Since Revatio has been released onto the market, there have been a few reports of bleeding in people who’ve taken the drug. However, there’s no evidence that Revatio caused these bleeding problems.

It’s not known if Revatio is safe for use by people with a bleeding problem. If you have any bleeding problems, talk with your doctor about whether Revatio is safe for you.

Dosage

Take one Revatio pill orally with a full glass of water, 30-60 minutes before sex. The dosage depends on the overall health of the patient. Do not take more than one pill per day. Take Revatio on an empty stomach, as fatty meals, grapefruit juice and alcohol can interfere with the effectiveness of the medication.

Overdose

If you overdose Revatio (Pfizer) and you don't feel good you should visit your doctor or health care provider immediately.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Side effects

The most common side effects associated with Revatio are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

You should not use Revatio if you are allergic to sildenafil, or:

if you take other medicines to treat pulmonary arterial hypertension, such as riociguat (Adempas). if you take nitrates.

Do not take Revatio if you are also using a nitrate drug for chest pain or heart problems. This includes nitroglycerin, isosorbide dinitrate, and isosorbide mononitrate. Nitrates are also found in some recreational drugs such as amyl nitrate or nitrite ("poppers"). Taking sildenafil with a nitrate medicine can cause a sudden and serious decrease in blood pressure.

To make sure Revatio is safe for you, tell your doctor if you have ever had:

heart disease or heart rhythm problems, coronary artery disease; a heart attack, stroke, or congestive heart failure; high or low blood pressure; liver or kidney disease; a blood cell disorder such as sickle cell anemia, multiple myeloma, or leukemia; a bleeding disorder such as hemophilia; a stomach ulcer; retinitis pigmentosa (an inherited condition of the eye); a physical deformity of the penis (such as Peyronie's disease); or if you have been told you should not have sexual intercourse for health reasons.

Revatio can decrease blood flow to the optic nerve of the eye, causing sudden vision loss. This has occurred in a small number of people taking sildenafil, most of whom also had heart disease, diabetes, high blood pressure, high cholesterol, or certain pre-existing eye problems, and in those who smoked or were over 50 years old. It is not clear whether sildenafil is the actual cause of vision loss.

Revatio is not expected to harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

It is not known whether sildenafil passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby.

Do not give this medicine to anyone under 18 years old without medical advice.

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COMPARATIVE EFFECTIVENESS OF SOME NEW GANGLION-BLOCKING AGENTS (PIPERIDINE DERIVATIVES) IN THE TREATMENT OF HYPERTENSIVE PATIENTS. Manufactured but not imported: new directions for research in shared decision making support and skills. Patients on units with CNSs had an overall shorter TLOS and fewer complications than did patients on units without CNSs, which is consistent with the literature. Metalloproteinases (MMPs) are essential regulators during various phases of the angiogenic process. Urinary exfoliative cytology in tumors of the kidney and ureter. The training intensity is self-adjusting based on fitness level allowing for an effective workout for different users. Subtractive hybridization was used in an attempt to identify genes that are preferentially expressed early in skeletogenesis. A linkage map for sugi was constructed on the basis of restriction fragment length polymorphism (RFLP), random amplified polymorphic DNA (RAPD), and isozyme loci using a three-generation pedigree prepared for genetic analysis of heartwood color. This review is a brief overview of the basic findings and a general classification of papillary carcinoma of the breast. From January 1, 2001, to June 30, 2002, 116 patients underwent isolated primary coronary artery bypass grafting.

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The change in how to take 500 mg zithromax specific airway conductance produced by smoking a cigarette under standard conditions was measured in 91 heavy smokers. Percutaneous transhepatic endobiliary brush cytology in detecting obstructive jaundice is evaluated. This method is particularly attractive for the generation of meta-substituted phenols bearing ortho-/para-directing groups, as such substrates are difficult to access by other phenol syntheses. Using a systematic approach to critical appraisal, a published RCT of treatments for severe depression is examined and evaluated. Evaluation of beta-cyclodextrin bonded silica as a selective sorbent for the solid-phase extraction of 4-nitrophenol and 2,4-dinitrophenol.

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Anemia is prevalent in heart failure and predicts mortality in men but not in women. Distribution and kinetics of lipoprotein-bound lipoteichoic acid. Annular pancreas concurrent with pancreaticobiliary maljunction presented with symptoms until adult age: case report with comparative data on pediatric cases. Natural skip oviposition of the mosquito Aedes aegypti indicated by codominant genetic markers. This led us to hypothesize that vitamin K supplementation may slow down the progression of calcification. In pit fields, cellulose microfibrils were arranged in circular patterns around plasmodesmata. However, to date, there are few studies on the effects of WBVT on energy metabolism and whether this tool could be able to enhance weight loss in addition to a nutritional plan and/or exercise.

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