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Cordaflex (Nifedipine)

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Cordaflex is used to treat hypertension (high blood pressure) and angina (chest pain). Cordaflex is in a class of drugs called calcium channel blockers. Cordaflex relaxes (widens) your blood vessels (veins and arteries), which makes it easier for the heart to pump and reduces its workload.

Other names for this medication:
Adalate, Addos, Adipine, Anpect, Atanaal, Atenerate, Buconif, Calcigard, Cardifen, Conducil, Coracten, Fenidina, Hexadilat, Marivolon, Menoprizin, Nedipin, Nifangin, Nifebene, Nifecap, Nifeclair, Nifecor, Nifedipinum, Niften, Nipin, Pressolat, Valni, Viscard

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Also known as: Nifedipine


Nifedipine is used alone or together with other medicines to treat severe chest pain (angina) or high blood pressure (hypertension). High blood pressure adds to the workload of the heart and arteries. If it continues for a long time, the heart and arteries may not function properly. This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure. High blood pressure may also increase the risk of heart attacks. These problems may be less likely to occur if blood pressure is controlled.

Nifedipine is a calcium channel blocker. It works by affecting the movement of calcium into the cells of the heart and blood vessels. As a result, nifedipine relaxes blood vessels and increases the supply of blood and oxygen to the heart while reducing its workload.

This medicine is available only with your doctor's prescription.


This section provides information on the proper use of a number of products that contain nifedipine. It may not be specific to Cordaflex OROS. Please read with care.

In addition to the use of this medicine, treatment for your high blood pressure may include weight control and changes in the types of foods you eat, especially foods high in sodium (salt). Your doctor will tell you which of these are most important for you. You should check with your doctor before changing your diet.

Many patients who have high blood pressure will not notice any signs of the problem. In fact, many may feel normal. It is very important that you take your medicine exactly as directed and that you keep your appointments with your doctor even if you feel well.

Remember that this medicine will not cure your high blood pressure, but it does help control it. You must continue to take it as directed if you expect to lower your blood pressure and keep it down. You may have to take high blood pressure medicine for the rest of your life. If high blood pressure is not treated, it can cause serious problems such as heart failure, blood vessel disease, stroke, or kidney disease.

Swallow the extended release tablet whole. Do not break, crush, or chew it. It is best to take this tablet on an empty stomach.

If you are taking the extended-release tablets, part of the tablet may pass into your stool after your body has absorbed the medicine. This is normal and nothing to worry about.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For treatment of chest pain or high blood pressure: For oral dosage form (capsules): Adults—At first, 10 milligrams (mg) three times a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor. For oral dosage form (extended-release tablets): Adults—At first, 30 or 60 milligrams (mg) once a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 90 mg once a day. Children—Use and dose must be determined by your doctor.


If you overdose Cordaflex and you don't feel good you should visit your doctor or health care provider immediately.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Detailed Nifedipine dosage information

Side effects

The most common side effects associated with Cordaflex are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

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Views of Cameroonian sex workers on a woman-controlled method of contraception and disease protection. Depending on the metal centers and the nature of the macrocyclic ligands, these compounds exhibit tunable spectroscopic, electronic, and redox properties, and different extents of intramolecular pi-pi interactions. Roles of muscularis mucosae and myofibroblasts in the healing process of acetic acid-induced ulcer. Using this structural and thermodynamic modeling approach, we show that multimer inter-subunit interface models can account for several experimental observations about ALLINI-induced multimerization, including large differences in the potencies of various ALLINIs, the mechanisms of resistance mutations, and the crucial role of solvent exposed R-groups in the high potency of certain ALLINIs. Purified GlyCAM-1 was found to support tethering and rolling in physiological shear flow of both human and murine L-selectin expressing leukocytes at an efficiency comparable to the HEV-derived L-selectin ligands termed peripheral node addressin (PNAd). Conservative treatment of neural arch fractures of the axis: computed tomography scan and X-ray study on consolidation time. Retrospective review: 102 patients with GCNI, MFPNI and MEPNI, observed or treated with RT from 2000 through 2013. System for secretion of heterologous proteins in Bacillus subtilis. Yet, once studied under conditions of shear stress when flowing along endothelial cells in vitro or in blood vessels, as well as in classic migration assays such as chemotaxis assays, MSCs have recently been found to function similarly to leukocytes in many ways. Blood pressure was normal in 56 patients and improved in 44 (mean follow-up, 69 and 59 months).

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The role of EVAR in women is poorly investigated and its definite role remains to be determined. Native MS has the capability to directly detect weak ligand binding to proteins, to determine stoichiometry, relative or absolute binding affinities and specificities. More research is required to identify the most cost-effective strategies for achieving maximum coverage of screening for all pregnant women, and access to treatment if required. An immunoconjugate (PF1/D-DAVLBHYD), made with the squamous carcinoma reactive monoclonal antibody PF1/D and a derivative of vinblastine, DAVLBHYD, was shown to suppress established T222 human tumor nude mouse xenografts using a multidose protocol. Resistant bacteria are one of the leading causes of hospital-acquired/ventilator-associated bacterial pneumonia (HABP/VABP). Elevated hydrostatic pressure enhances the motility and enlarges the size of the lung cancer cells through aquaporin upregulation mediated by caveolin-1 and ERK1/2 signaling. The aim of this study was to explore the role of cytokines in the pathogenesis of SLE in a genetically homogeneous Caucasian SLE patient population. In terms of histological extension, lymph node metastasis or vascular and nerve invasion is not found in m cancer, but in some cases of mp cancer vascular invasion is present. Periodic electrical excitation induced periodic resistive heating in the cantilever, while the cantilever deflection was monitored with a photodetector.

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Potential implications of the harmful dysfunction analysis for the development of DSM-V and ICD-11. Postnatal eNRG1 treatment significantly enhanced polysynaptic IPSCs, although monosynaptic IPSCs were not affected. It has selected for those pathogens, mainly microorganisms but also parasites, that have evolved countermeasures. Adenosine deaminase attenuates canine coronary vasodilatation during regional non-ischaemic myocardial hypoxia. We aim to review data from published studies in order to examine the association between CIMP and CRC prognosis. Maternal first-trimester iodine deficiency predicts poor cognitive outcome in English children. In this comparison, magnetic bead column separation of 7G8 schizonts resulted in higher viability and efficiency of invasion than utilizing Percoll gradient centrifugation. A prototype Tay-Sachs disease prevention program is presented and di scussed. Tetrodotoxin, which blocks the voltage-sensitive sodium channel, was used to prevent action potentials. However, molecular targeting of these alterations individually has yielded disappointing results.

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Although jaundice rarely complicates polycystic liver disease (PLD), secondary benign or malignant causes cannot be excluded. Protein-drug interactome analysis of SSRI-mediated neurorecovery following stroke. This review describes recent findings of how defects in paracellular chloride permeation pathway may cause kidney diseases and how such a pathway may be regulated to maintain normal chloride homeostasis. Epithelial proliferation, wound healing, and resistance to oxidative stress-induced apoptosis were assessed, as was colonic motility. Mitochondrial biogenesis and angiogenesis in skeletal muscle of the elderly.

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Quantification of isoflavones by capillary zone electrophoresis in soybean seeds: effects of variety and environment. Dual-modulation, dual-wavelength, optical polarimetry system for glucose monitoring. After one month culture, the transformed mesenchymal cells exhibited the morphology and phenotype similar to those of tumor cells, and also caused multiple fast growing lung deposits when it was injected into immunodeficient mice. Post-transplant diabetes mellitus in pediatric liver transplantation. During the second phase, a continuous basement membrane is being laid down around the hyaloid capillaries, zonular fibres appear in close contact with the lens capsule and retinal basement membrane, a very dense afibrillar material begins to fill up the lens periequatorial area. Brivanib attenuates hepatic fibrosis in vivo and stellate cell activation in vitro by inhibition of FGF, VEGF and PDGF signaling. Thus the sites of viral DNA replication and late transcription coreg medicine appear to be distinct but codistribute within the boundaries of replication compartments. Currently cardiovascular diseases (CVDs) are the main cause of death worldwide. Moclobemide, a new selective and reversible inhibitor of monoamine oxidase A (RIMA), has been compared with various tricyclic antidepressants (TCAs) in numerous controlled studies. Here, we use the logistic regression and support vector machine to discriminate between two-state and multi-state folding proteins.

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