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Alprogard (Alprazolam)

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Alprogard is a potent, short-acting benzodiazepine anxiolytic—a minor tranquilizer. It is commonly used for the treatment of anxiety disorders, especially of panic disorder. It's also used in the treatment of generalized anxiety disorder (GAD) or social anxiety disorder. It was the 12th most prescribed medicine in the United States in 2010. Alprogard, like other benzodiazepines, binds to specific sites on the GABAA receptor. It possesses anxiolytic, sedative, hypnotic, skeletal muscle relaxant, anticonvulsant, amnestic, and antidepressant properties. Alprogard is available for oral administration as compressed tablets (CT) and extended-release capsules (XR).

Other names for this medication:
Aldep, Alparazole, Alpose, Alpron, Alzom, Ambusyn, Cardilax, Coolam, Depten, Dexolam, Diprex, Elflu, Golprax, Hiprazole, Kurelam, Mebrin, Onapract, Optizole, Paxor, Plxna, Pranol, Restam, Sinozol, Sinzolam, Tenan, Tenscure, Trazopin, Viprax, Wycalm, Zedel, Zeecam, Zeftra, Zocam, Zorest

Similar Products:
Vantin, Urispas, Eulexin, Motilium, Persantine, Cleocin, Lozol, Arava, Elocon, Effmin, Azitral, Awnacid, Valpret, Pacinac, Bioxel,

Also known as: Alprazolam


Alprogard XR (alprazolam) is in a group of drugs called benzodiazepines (ben-zoe-dye-AZE-eh-peens). Alprazolam affects chemicals in the brain that may become unbalanced and cause anxiety.

Alprogard XR is used to treat anxiety disorders, panic disorders, and anxiety caused by depression.

Alprogard XR may also be used for other purposes not listed in this medication guide.


Usual Adult Dose for Anxiety:

Immediate-release tablets: 0.25 to 0.5 mg orally administered 3 times a day -Maximum dose: 4 mg/day

Usual Adult Dose for Panic Disorder:

Immediate-release tablets: 0.5 mg orally administered 3 times a day -Maximum dose: 10 mg/day Extended-release tablets: -Initial dose: 0.5 to 1 mg orally once a day -Maintenance dose: 3 to 6 mg orally per day, preferably in the morning -Maximum dose: 10 mg/day Comments: -The lowest possible effective dose should be administered and the need for continued treatment reassessed frequently. -Dosage should be reduced gradually when discontinuing therapy or when decreasing the daily dosage. -The daily dosage may be decreased by no more than 0.5 mg every 3 days; however, some patients may require an even slower dosage reduction. -The dose of extended-release tablets may be increased at intervals of 3 to 4 days in increments of no more than 1 mg per day. -The times of administration should be distributed as evenly as possible throughout the waking hours.

Usual Geriatric Dose for Anxiety:

Elderly or debilitated patients: Immediate-release tablets: 0.25 mg orally administered 2 or 3 times a day.

Usual Geriatric Dose for Panic Disorder:

Elderly or debilitated patients: Immediate-release tablets: -Initial dose: 0.25 mg orally administered 2 or 3 times a day Extended-release tablets: -Initial dose: 0.5 mg orally once a day Comments: -If side effects develop, the dose may be lowered. -The lowest possible effective dose should be administered and the need for continued treatment reassessed frequently. -Dosage should be reduced gradually when discontinuing therapy or when decreasing the daily dosage.

Detailed Alprogard dosage information


If you have been prescribed Alprogard for medical reasons, the best way to avoid a Alprogard overdose is to adhere to prescribed orders—closely monitor your dose and the time at which you take your medication. Track your Alprogard consumption in a notebook or on your phone. If you notice that you are taking a higher dose of the drug, taking the drug more often, or you want to consume more of the drug, talk with your doctor immediately.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

It is very important to protect the orally disintegrating tablets from moisture. Remove and throw away any cotton packaging from the medicine bottle when you first use the medicine.

Detailed Alprogard dosage information

Side effects

The most common side effects associated with Alprogard are:

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