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Alpra (Alprazolam)

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Alpra is commonly used to treat anxiety and panic disorders. It falls into a category of medications called benzodiazepines. They are known to affect the central nervous system components and produce a calming effect, thus decreasing brain activity.

Other names for this medication:
Alpracon, Alrif, Ansilumirm, Anxicalm, Cozac, Deproz, Depwell, Dipra, Elzopam, Faxtin, Fludep, Fluprax, Isorest, Plxna, Prolam, Resta, Romipraz, Somnia, Sozox, Viprax, Zeecam, Zolam, Zolent, Zolin, Zotin

Similar Products:
Robaxin, Abhigra, Rocaltrol, Valtrex, Cipro, Zyprexa, Aristocort, Cefolex, Exprex, Azimed, Nifedine, Vigia, Supres, Sycored,

Also known as: Alprazolam


Alpra (alprazolam) is a benzodiazepine (ben-zoe-dye-AZE-eh-peen). It is thought that alprazolam works by enhancing the activity of certain neurotransmitters in the brain.

Alpra is used to treat anxiety disorders and anxiety caused by depression.

Alpra is also used to treat panic disorders with or without a fear of places and situations that might cause panic, helplessness, or embarrassment (agoraphobia).

It is dangerous to purchase Alpra on the Internet or outside the United States. The sale and distribution of medicines outside the U.S. does not comply with safe-use regulations of the Food and Drug Administration (FDA). These medications may contain dangerous ingredients, or may not be distributed by a licensed pharmacy.


This section provides information on the proper use of a number of products that contain alprazolam. It may not be specific to Alpra. Please read with care.

Take this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. If too much of this medicine is used for a long time, it may become habit-forming (causing mental or physical dependence) or cause an overdose.

This medicine should come with a Medication Guide. Read and follow the instructions carefully. Ask your doctor if you have any questions.

Swallow the extended-release tablet or tablet whole with a full glass of water. Do not break, crush, or chew it.

If you are using the orally disintegrating tablet, make sure your hands are dry before you handle the tablet. Do not remove the tablets from the bottle until you are ready to take it. Place the tablet immediately on the top of your tongue. It should melt quickly and be swallowed with saliva.

If you are using the oral liquid, measure the dose with a marked measuring spoon, oral syringe, or medicine cup.

Do not eat grapefruit or drink grapefruit juice while you are using this medicine.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For anxiety: For oral dosage forms (solution, tablets, or orally disintegrating tablets): Adults—At first, 0.25 to 0.5 milligram (mg) 3 times a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 4 mg per day. Older adults—At first, 0.25 mg 2 or 3 times a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor. For panic disorder: For oral dosage form (extended-release tablets): Adults—At first, 0.5 to 1 milligram (mg) taken in the morning once a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 10 mg per day. Older adults—At first, 0.5 mg taken in the morning once a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor. For oral dosage forms (solution, tablets, or orally disintegrating tablets): Adults—At first, 0.5 milligram (mg) 3 times a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 10 mg per day. Older adults—At first, 0.25 mg 2 or 3 times a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor.


Seek emergency medical attention if you think you have used too much of this medicine. An overdose of Alpra XR can be fatal.

Overdose symptoms may include extreme drowsiness, confusion, muscle weakness, loss of balance or coordination, feeling light-headed, fainting, and coma.


Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company for more details.

Side effects

The most common side effects associated with Alpra are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Before taking Alpra, tell your doctor or pharmacist if you are allergic to it; or to other benzodiazepines (such as diazepam, lorazepam); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.Before using this medication, tell your doctor or pharmacist your medical history, especially of: severe lung/breathing problems (such as COPD, sleep apnea), liver disease, kidney disease, drug or alcohol abuse, glaucoma.This drug may make you dizzy or drowsy. Do not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely. Avoid alcoholic beverages.Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).Older adults may be more sensitive to the side effects of this drug, especially loss of coordination and drowsiness. These side effects can increase the risk of falling Alpra is not recommended for use during pregnancy due to the potential for harm to an unborn baby. Consult your doctor for more details.This drug passes into breast milk and may have undesirable effects on a nursing infant. Therefore, breast-feeding while using this drug is not recommended. Consult your doctor before breast-feeding.

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Platelet activating factor induces transient blood-brain barrier opening to facilitate edaravone penetration into the brain. Visual impairment corrected via cataract surgery and 5-year survival in a prospective cohort. Ballistocardiographic study of a group of patients with chronic lung disease. Cassava leaves, consumed in large amounts by aborigines, probably caused goitres by decreasing iodine absorption. The mdx mouse is a responsive system for the screening of potential therapeutic treatments for the muscular dystrophies. Current hematologic and biochemical markers of iron status in the dog are insensitive, and results may be highly variable, especially in the presence of concurrent disease (ie, inflammation, neoplasia). This study assesses the residual effects of combined MDMA/THC use, and of THC use alone, upon perceived trajectory of travel. Validation of the bispectral index monitor during conscious and deep sedation in children. A variety of skin disorders have been associated with HES, although there are no previous reports of HES associated with cutaneous infarction.

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Newly available short acting and long acting (depot) antipsychotics complement oral antipsychotics so that the full spectrum of routes of administration is now available for second generation antipsychotics. We define the outcomes and the prognostic factors that influenced the final visual acuity and globe survival in patients with IOFBs that we extracted by pars plana vitrectomy (PPV) over a 5-year period. Hyperactivity in patients with anorexia nervosa and in semistarved rats: evidence for a pivotal role of hypoleptinemia. These observations extend the role of taurine from the regulation of cell volume to that of the whole body fluid balance. Establishment of a porcine cell line from in vitro-produced blastocysts and transfer of the cells into enucleated oocytes. In the first of two stages of this procedure, an estimate of the average stimulus artifact is calculated from traces of multiple stimulations at the same site. To clarify the role of MKP-1, we determined the effects on the MAPKs and cell growth and death in primary fibroblasts derived from mice lacking MKP-1. Simultaneous determination of endocannabinoids (arachidonylethanolamide and 2-arachidonylglycerol) and isoprostane (8-epiprostaglandin F2alpha) by gas chromatography-mass spectrometry-selected ion monitoring for medical samples.

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Retinoids have many pharmacological activities, including anti-inflammatory action and antiangiogenesis, effected through the regulation of various gene transcriptions. Genotypes were determined by allele-specific polymerase chain reaction and the GeneChip microarray technique. To assess public attitudes towards the fortification of flour with folic acid, and quantify their intensity of preference towards the proposed policy. Engineered bacterial plasmids containing a cytomegalovirus promoter (CMV)-IL-2 expression cassette were specifically formulated with cationic lipids and optimized for antitumor effect in a floor of mouth murine tumor model. The methods of synthesis and properties of prophyrins covalently linked with carbohydrates are considered. Ultrasonograms showed a lobular (5 of 9) or an oval (4 of 9) shaped mass with a circumscribed margin (9 of 9). Although corticosteroid is the mainstay of therapy for polymyositis, our case study showed that IVIG is also an efficacious therapy for polymyositis, especially resistant to the conventional treatment.

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A contribution to the innervation of the urinary bladder of the cat. The findings suggest that at least some of the high grade gastric lymphomas, especially in patients younger than the fifth decade, do not originate from high grade transformation of low MALT lymphomas. The authors report a case of a lipomyelomengocele with tethered cord, revealed on prenatal ultrasonography and confirmed by fetal magnetic resonance imaging (MRI). Threatening spinal cord compression during anesthesia in a child with mucopolysaccharidosis VI. Elsewhere, pentavalent antimonials remain the cornerstone of treatment in non resistant areas, conventional amphotericin B or miltefosine being an alternative in areas of resistance to antimony. Manual and computer-assisted searches were conducted to find the articles published on this topic during the 30-year period from 1970 to 2000. TREATMENT STRATEGIES FOR ELDERLY PATIENTS WITH NEWLY DIAGNOSED MULTIPLE MYELOMA: A META-ANALYSIS AND INDIRECT TREATMENT COMPARISON. Changes in nuleic acid concentrations in some organs of growing male rats and their influencing by cyproterone acetate and testosterone.

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The dramatic alterations in the appearance of the integument with increasing age are due in part to a progressive destruction of the delicate architecture of the connective tissue components of the dermis. Barium solutions can be considered to elicit behaviors that are similar to those used with nonbarium liquids outside the assessment situation. Two hundred five Procera AllCeram crowns (50 anterior and 155 posterior) were evaluated in a prospective study from a minimum of 6 months to a maximum of 60 months, with a mean of 23.52 months. We compare the secondary olfactory projections in hagfishes with those in lampreys and in gnathostomes, and we conclude that the presence of extensive secondary olfactory projections is a primitive character of craniate brains. Postnatal changes in bacterial populations in the gastrointestinal tract of dogs. Characterization of recombinant human DNA topoisomerase IIIalpha activity expressed in yeast. SDS/PAGE revealed that the product isolated from the culture medium comprised an approx, 7:3 mixture of two different forms of proteinase A, the apparent molecular masses of which were 42 and 40 kDa respectively. Physician narratives provide a unique perspective on the natural history of IOPD and are useful adjuncts to other data collection.

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Capturing reimbursement for advanced practice nurse services in acute and critical care: legal and business considerations. From emerging viruses to cardiovascular disease: preventive measures matter. For toxicological reasons, these carriers and their degradation byproducts are undesirable for inhalation therapy, particularly for chronic use, due to potential lung accumulation. This suggests a trade-off between positive and negative effects, where the initial increase may hinge upon several factors such as energy subsidising, screening of UV-radiation or P and N load being associated with organic carbon. To examine the effects of vegetation cover on the resprouting abilities of Quercus crispula seedlings, in each of three consecutive years, we artificially clipped seedlings growing in microhabitats with differing degrees of vegetation cover. Ghrelin activates neuronal constitutive nitric oxide synthase in pancreatic islet cells while inhibiting insulin release and stimulating glucagon release. Recently, an association between obesity and periodontal disease was found in a Japanese population. Single photon emission computed tomography (SPECT) for regional blood flow and/or magnetic resonance imaging (MRI) were also performed. polygyrus-infected GATA-3-transgenic mice exhibited significantly more peripheral blood eosinophils and total IgE levels compared with control mice.

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Bone loss in AN may not be completely reversible despite recovery from the illness. Identification of genes differentially expressed in melanoma sublines derived from a single surgical specimen characterised by different sensitivity to cytotoxic T-lymphocyte activity. Notwithstanding such effects and potential thermoregulatory capabilities, stingless bees show niche differentiation and biogeographic distributions that correlate with body coloration and body size. Our objective was to assess a novel operative combination of laparoscopic ultrasound (LUS) with laparoscopic radiofrequency (LRF) in the treatment of HCC not amenable to liver resection. New infrared technique for the determination of impurity in substituted anthranilic acid: effect of ortho substitution on the aromatic acid carbonyl band. Effect of electrical stimulation of the carotid sinus on venomotor tone of the superior vena cava in dogs. thirty patients with mild to moderate essential hypertension (15 without echocardiographic evidence of LVH and 15 with LVH) and 15 athletes with LVH were studied. Ganglions of the wrist: proposals for topographical systematization and natural history. Our report demonstrates that anonymous factors produced by feeder cells are not necessary for hESC maintenance and subsequent hematopoietic specification, thereby providing a defined system for studies of hESC self-renewal and hESC-derived hematopoiesis.

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The Hospital del Mar criteria need to be modified for some of the motions. These findings indicate that mCIA-II expression in testis is restricted to premeiotic to meiotic stages during spermatogenesis. Microbial contamination of dialysate and its prevention in haemodialysis units. This coincided with the formation of germinal centers (GC) and Th2 type of interleukins in spleen as reported earlier. Methods of inducing the tolerance state and its influence on the course of asthma and rhinosinusitis. We report a case associated with partial malrotation of the gut which has not been described in the literature before. All populations increase metabolic rate in response to increasing amounts of live dietary yeast. PNE resulted in a decreased likelihood of jumping during the elevated platform test and decreased directed exploration in the Suok test, both indicative of increased anxiety. These findings provide useful guidance for family doctors training and health service planning in Europe. The agents responsible for the excess cancer risk in some industrial settings have also been identified, as well as the mechanisms by which numerous occupational risk factors play a role in the various steps of the multifactorial carcinogenic process.

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Phytoremediation: an overview of metallic ion decontamination from soil. A multisensor array has been previously developed for implantation in a hamster skinfold window chamber preparation to study these effects. There has been a controversy regarding occupation, as defined by blue and white collar work, and coronary heart disease (CHD). The task appears to provide a robust measure of inhibitory function across the age range, 3 to 16 years. Isolation and expression of lactate dehydrogenase genes from Rhizopus oryzae. Preliminary ultrasound assessed site, size, echoic appearance and margins of the lesion. ticlopidine brand names However, three-dimensional (3D) localization of high-density data remains challenging since PSFs are far more similar along the axial dimension than the lateral dimensions. The prognosis of patients with malignant lymphoma discovered in the localized state and adequately treated is excellent. To address these questions, we evaluated cell proliferation using a monoclonal antibody to Ki-67 (a cell-cycle marker) and apoptosis using the in situ end-labeling method (TUNEL) on paraffin-embedded placental tissues.

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Experimental studies of the effect of antituberculous drugs on tuberculous otitis in guinea pigs. This strategy has showed that several polymorphisms of the beta1 and beta2 adrenergic receptors genes and the angiotensin converting enzyme gene are correlated to the prognosis of patients with heart failure. Escape from Mitotic Arrest: An Unexpected Connection Between Microtubule Dynamics and Epigenetic Regulation of Centromeric Chromatin in Schizosaccharomyces pombe. ITR1 mRNA abundance decreases when cells are transferred from medium without inositol to medium with inositol. As similarly sulfated compounds were ineffective in vivo, the data also underscore the fact that polysaccharides with similar structures may elicit diverse in vivo effects. The transcription factors c-Fos and c-Jun have been described to be overexpressed following many pathological stimuli, but whether they are required for neurodegeneration or neuroprotection is still open.

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Moreover, the articles showed that immune response is a crucial determinant of prognosis in the HER2-positive and estrogen receptor-negative/HER2-negative subtypes, providing a rationale to further explore the role of the antitumor immune response in these breast cancer subtypes. There was no significant correlation between change in visual acuity after PDT and amplitude of the multifocal ERG. S-1 in the treatment of advanced and recurrent gastric cancer: current state and future prospects. This brief review aims to demonstrate the relevance of changes in blood pressure and large artery structure and function occurring after menopause. Patients with central venous stenosis or occlusion had simultaneous angioplasty and stenting as indicated. Effect of acute sublethal endotoxaemia on in vitro digital vascular reactivity in horses. A sample of 2110 subjects aged 35-44 years were examined between September 1994 and July 1995, throughout the province of Quebec, Canada. Our preliminary results indicate that some MODY genes could suggest pathways whereby the changes occur and that epigenetic changes during development are involved. Several signalisation factors (cytokines and chemokines) are implicated in activation of mast cells receptors.

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