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Alendronate

Alendronate is used to prevent and treat certain types of bone loss (osteoporosis) in adults. Osteoporosis causes bones to become thinner and break more easily. This medication works by slowing bone loss. Alendronate belongs to a class of drugs called bisphosphonates.

Other names for this medication:
Alant, Alendix, Alendronate, Alenost, Bifosa, Denfos, Osteofos, Ostogee, Poronil, Ralenost, Restofos, Zophost

Similar Products:
Furadantin, Hytrin, Zocor, Imodium, Diflucan, Diamox, Asacol, Xalatan, Xputum, Clobetamil, Zurocid, Ezetib, Levozine,

Description

Alendronate Plus D contains a combination of alendronate and cholecalciferol. Alendronate is a bisphosphonate medicine that alters bone formation and breakdown in the body. This can slow bone loss and may help prevent bone fractures.

Cholecalciferol is a form of vitamin D, and is important for the absorption of calcium from the stomach and for the functioning of calcium in the body.

Alendronate Plus D is used to treat and prevent osteoporosis.

Dosage

Take Alendronate exactly as prescribed by your doctor. Alendronate is taken either once daily or once per week. Follow all directions on your prescription label. Do not take this medicine in larger or smaller amounts or for longer than recommended.

Take Alendronate first thing in the morning, at least 30 minutes before you eat or drink anything or take any other medicine. If you take this medicine only once per week, take it on the same day each week and always first thing in the morning.

Take with a full glass (6 to 8 ounces) of plain water. Do not use coffee, tea, soda, juice, or mineral water. Do not eat or drink anything other than plain water.

Do not crush, chew, or suck on an Alendronate tablet. Swallow the tablet whole.

For at least 30 minutes after taking Alendronate:

Do not lie down or recline. Do not take any other medicine including vitamins, calcium, or antacids.

Pay special attention to your dental hygiene while taking Alendronate. Brush and floss your teeth regularly. If you need to have any dental work (especially surgery), tell the dentist ahead of time that you are using alendronate.

Alendronate is only part of a complete program of treatment that may also include diet changes, exercise, bone mineral density testing, and taking calcium and vitamin supplements. Follow your doctor's instructions very closely.

Store at room temperature away from moisture and heat.

Your doctor will determine how long to treat you with this medicine. Alendronate is often given for only 3 to 5 years.

Detailed Alendronate dosage information

Overdose

If you overdose Generic Alendronate and you don't feel good you should visit your doctor or health care provider immediately. Symptoms of Generic Alendronate overdosage: heartburn, stomach pain, diarrhea, numbness, tingling, tight muscles in your face, irritability, unusual thoughts or behavior, nausea, muscle cramps, convulsions.

Storage

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Alendronate are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

You should not take Alendronate Plus D if you have low levels of calcium in your blood (hypocalcemia), or a problem with the movement of muscles in your esophagus.

Do not take a Alendronate Plus D tablet if you cannot sit upright or stand for at least 30 minutes. Alendronate can cause serious problems in the stomach or esophagus (the tube that connects your mouth and stomach). You will need to stay upright for at least 30 minutes after taking Alendronate Plus D.

To make sure Alendronate Plus D is safe for you, tell your doctor if you have:

low blood calcium (hypocalcemia); a cancer such as sarcoidosis, leukemia, lymphoma; a vitamin D deficiency; kidney disease; or an ulcer in your stomach or esophagus.

In rare cases, this medicine may cause bone loss (osteonecrosis) in the jaw. Symptoms include jaw pain or numbness, red or swollen gums, loose teeth, or slow healing after dental work. The longer you use Alendronate Plus D, the more likely you are to develop this condition.

Osteonecrosis of the jaw may be more likely if you have cancer or received chemotherapy, radiation, or steroids. Other risk factors include blood clotting disorders, anemia (low red blood cells), and a pre existing dental problem.

Talk with your doctor about the risks and benefits of using this medication.

It is not known whether Alendronate Plus D will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication.

It is not known whether alendronate and cholecalciferol passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby.

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Heparin/HS are complex mixtures displaying extensive structural diversity. To define the differences between lower extremity biomechanics (knee abduction and knee flexion measures) and performance (maximal vertical jump height) between National Collegiate Athletic Association Division I and III female soccer athletes during a drop vertical jump. Extraction followed by liquid chromatography-tandem mass spectrometry (LC-MS/MS) analysis is the method of choice when it comes to the accurate quantification of 25-OH-vitamin D in blood samples. Linearized quantum-fluctuation theory of spectrally filtered optical solitons. The recent addition of tandem mass spectrometry (MS/MS) resulted in a fivefold increase in the number of tests. Concentrations of heavy metals in one bird were 0.25 microgram of total mercury and 0.5 microgram of lead/g of liver, respectively. Thus, the mechanism by which methotrexate suppresses disease activity in RA but not in MS despite both being T-cell mediated autoimmune diseases requires further investigative studies. Hydatid cyst superinfection, intrabiliary rupture, and direct rupture into the thoracic or abdominal cavities are the frequently encountered complications. Further insights into the importance of treatment culture will be pursued in qualitative studies. Mycobacterial antigens stimulate rheumatoid mononuclear cells to cartilage proteoglycan depletion.

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Colocalization of the PTH1R, NPT2a, and ezrin exists and is prominently associated with actin-containing microvilli in apical domains of these cells. The median time span between symptom onset and diagnosis in our study was 24 days. The application of Fourier-transform Raman spectroscopy to the analysis of pharmaceuticals and biomaterials. When the periodicity of seizure exacerbation aligns itself with that of the menstrual cycle, it is designated as catamenial epilepsy. Self-identified tobacco use increases the risk of a SGA infant at term across maternal strata. Relatively strong positive or negative affective reactions resulted in less desirability bias. The presence of J chain was represented in 113 specimens after acid-urea pretreatment.

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