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Afeditab (Nifedipine)

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Afeditab is a calcium-channel blocker. It affects the amount of calcium found in your heart and muscle cells. This relaxes your blood vessels, which can reduce the amount of work the heart has to do. This medicine is used to treat chest pain caused by angina.

Other names for this medication:
Adalate, Afeditab, Atanaal, Calcianta, Calcigard, Cardalin, Cardicon, Cardiosol, Casanmil, Cisday, Citilat, Cobalat, Cordalat, Cordilat, Cordipin, Emaberin, Epilat, Fedip, Ficard, Hexadilat, Menoprizin, Myogard, Nicardia, Nidilat, Nifangin, Nifcal, Nifecap, Nifeclair, Nifecor, Nifedate, Nifedip, Nifedipress, Nipidin, Tensopin, Xepalat, Zenusin

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Also known as: Nifedipine


Nifedipine is used alone or together with other medicines to treat severe chest pain (angina) or high blood pressure (hypertension). High blood pressure adds to the workload of the heart and arteries. If it continues for a long time, the heart and arteries may not function properly. This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure. High blood pressure may also increase the risk of heart attacks. These problems may be less likely to occur if blood pressure is controlled.

Nifedipine is a calcium channel blocker. It works by affecting the movement of calcium into the cells of the heart and blood vessels. As a result, nifedipine relaxes blood vessels and increases the supply of blood and oxygen to the heart while reducing its workload.

This medicine is available only with your doctor's prescription.


This section provides information on the proper use of a number of products that contain nifedipine. It may not be specific to Afeditab PA 20. Please read with care.

In addition to the use of this medicine, treatment for your high blood pressure may include weight control and changes in the types of foods you eat, especially foods high in sodium (salt). Your doctor will tell you which of these are most important for you. You should check with your doctor before changing your diet.

Many patients who have high blood pressure will not notice any signs of the problem. In fact, many may feel normal. It is very important that you take your medicine exactly as directed and that you keep your appointments with your doctor even if you feel well.

Remember that this medicine will not cure your high blood pressure, but it does help control it. You must continue to take it as directed if you expect to lower your blood pressure and keep it down. You may have to take high blood pressure medicine for the rest of your life. If high blood pressure is not treated, it can cause serious problems such as heart failure, blood vessel disease, stroke, or kidney disease.

Swallow the extended release tablet whole. Do not break, crush, or chew it. It is best to take this tablet on an empty stomach.

If you are taking the extended-release tablets, part of the tablet may pass into your stool after your body has absorbed the medicine. This is normal and nothing to worry about.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For treatment of chest pain or high blood pressure: For oral dosage form (capsules): Adults—At first, 10 milligrams (mg) three times a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor. For oral dosage form (extended-release tablets): Adults—At first, 30 or 60 milligrams (mg) once a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 90 mg once a day. Children—Use and dose must be determined by your doctor.


If you overdose Afeditab and you don't feel good you should visit your doctor or health care provider immediately.


Store at room temperature between 15 and 25 degrees C (59 and 77 degrees F) away from moisture and heat. Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

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Studies in women suggest that this medication poses minimal risk to the infant when used during breastfeeding.

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Aerotolerance of strictly anaerobic microorganisms and factors of defense against oxidative stress: a review. Thus, stored red blood cells (RBCs) become less deformable and more fragile as they age. The main clinical findings were unopposed remaining teeth, overeruption of the remaining teeth, loss of vertical dimension of occlusion, and significant disfigurement of the occlusal plane. The results not only demonstrate that stabilized whole PNH blood samples are suitable for use with currently recommended high-sensitivity reagent cocktails/protocols but also highlight the importance of using carefully selected conjugates alongside the standardized protocols. The purpose of this study was to explore the natural history of VBD, evaluate its progression, and examine factors that may influence the clinical course of this condition. Subsequently, real-time PCR was performed to validate eight differentially expressed genes screened out by the microarray approach and sufficient consistency was observed between the two methods.

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Conservative management of a chylothorax in a 57-year-old man was unsuccessful (25 l chylous fluid removed over three weeks). Assessing the Dependability of Drinking Motives via Generalizability Theory. Contrary, Fe hepatic cytosolic concentrations were significantly lower in specimens from spring than in autumn period. Binding of IgG antibodies to platelet protein antigens was observed in 39 of the 71 patients. The expression of MMP-2, MMP-9, and E-cadherin in the endometrium prior to IVF treatment was not associated with pregnancy. The changed expression pattern correlated with the alteration of a single base pair in the long terminal repeat of the lymphoid cell-specific virus. Interleukin-1 release by rat synovial cells is dependent on sequential treatment with gamma-interferon and lipopolysaccharide. In general, NaCl extracts were highly enriched for cellular proteins and GuHCl extracts were predominantly matrix components, with some interesting exceptions. Importantly, GSSE prevented all the deleterious effects of HFD treatment.


Only one of the samples of normal urothelium obtained from 16 different tumor-bearing bladders was positive for MUC7 gene expression. This new Angelman syndrome iPSC line allows to study imprinted gene regulation on both parental alleles and to dissect molecular pathways affected by the absence of UBE3A protein. We administered pointing tasks, using 90 line drawings representing single nouns. The cell wall, composed of a simple meshwork of long glycan strands crosslinked by short peptides (peptidoglycan, PG) and anionic cell wall polymers such as wall teichoic acids (WTAs), is the major determinant of cell shape. Ecotypic differences demonstrate how responses to environmental stimuli are differently regulated to survive a particular habitat. Publication output in Germany, Austria and Switzerland has decreased. The accuracy of the printed model is determined by the quality of organ models and 3DP. In this study, specific drugs that influence AA metabolism were investigated for their effects on brain edema and energy metabolites during ischemia. In most patients an increase of mean right atrial pressure up to 10-14 mm Hg was followed by an increase in right ventricular stroke work index.

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Insulin-like growth factor-I and insulin were less effective than equimolar concentrations of GH in inducing c-fos expression. Treatment also reduced lipid peroxidation and increased anti-oxidant parameters in the liver homogenates of diabetic rats. Ontogeny of beta B1-crystallin polypeptide during chicken lens development. Analysis of green pit viper (Trimeresurus alborabris) venom protein by LC/MS-MS. Shigellosis is one of the major causes of morbidity in children with diarrhea in Iran.

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Mobitz type II second-degree block manifests with several consecutive impulses conducted with a constant conduction time that are followed by block. We show how both proportions and rarefied counts result in a high rate of false positives in tests for species that are differentially abundant across sample classes. This is accomplished by doping a commercial chemically amplified photoresist (SU-8) with an absorbing dye to provide thermal activation at a wavelength shifted from that causing UV crosslinking. PRR non-proteolytically activates prorenin and its role has attracted the attention of researchers towards the RA system. On the other hand, histological study of the high-phosphorus diet group at 4 weeks after implantation still showed a meaningful amount of the osteoid matrix formation compared to the control. The monitoring of the results of laboratory control over the quality of drinking-water and the assessment of health risk enabled a package of measures to be proposed to optimize the conditions of drinking water supply in the Vologda Region. Illustrating the Multi-Faceted Dimensions of Group Therapy and Support for Cancer Patients. Here we show that stable hydrogen (deltaD) and carbon (delta13C) isotope ratios of wintering monarchs can be used to evaluate natal origins on the summer breeding range.

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We reviewed the slides of 767 patients with TNBC and evaluated the TIL levels. In vivo peripheral quantitative computerized tomography (pQCT) of the proximal tibial metaphyses (PTM) and ex vivo histomorphometric analyses of the PTM and tibial shaft (TX) were performed. The usual circumstances leading to fracture of the pisiform bone include fall with reception on the hyperextended wrist, traffic accidents, and blunt trauma. Orthodontic retraction of autotransplanted premolar to replace ankylosed maxillary incisor with replacement resorption. It is known that the intrinsic ability of CNS neurons to survive and to regrow axons after optic nerve injury differs between developing and adult mammals. Important features of a screening program with breast MR imaging include the following: optimization of the MR imaging technique, an awareness of the imaging features of invasive and noninvasive breast cancers detected with MR imaging, an understanding of the limitations of the various imaging modalities in both the initial screening and subsequent diagnostic work-up evaluations, and the requirement for MR imaging-guided biopsy. Serotonin (5-HT) receptors may have a role in suicidal behavior. Since nuclear factor kappaB (NF-kappaB) has been implicated in the control of chemokine transcription and cell proliferation, we also investigated its activation and localization in the lesion. putida KT2440 were eluted in the range of pH 4.8-6.0 in FFE, whereas the denatured proteome of P.

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As the industry expands this has raised concern about the potential for toxicological effects on ecosystems, workers, and the general public. Salmonella enterica serotype I 3,10: r:- and Salmonella enterica serotype Weltevreden were the most commonly isolated non-Typhi serotypes. At the end of each treatment, blood pressure, AFV, PSTP, plasma renin activity (PRA) and norepinephrine were assessed. In addition, some developed nations are currently undergoing a dramatic shift in healthcare delivery, resulting in millions of patients nursed at home. A combination of protein crystallography and biochemistry has revealed how a ring-shaped helicase might trap a single DNA strand as the double helix melts, and before it is unwound. In contrast to animals, plant gametes form in distinct haploid generations, termed gametophytes. A combination of a mengioma of the optic nerve and a spongioblastoma of the retina.

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Next, we examined the influence of loperamide administration on the intestinal mucosa and plasma PYY concentrations in these rats. Involvement of the optic pathways is not a frequent finding in GBS. From liquids to NLRO and further to ELRO, the five-fold symmetry of these polyhedra gradually fades, and finally vanishes when B2 structure is distributed throughout the grain bulk. The optimal working temperature of the enzyme was around 46 degrees C. Prevalence of Depression, Anxiety and Stress as Measured by the Depression, Anxiety, and Stress Scale (DASS-42) among Secondary School Girls in Abha, Saudi Arabia. Gene therapy and virotherapy are one of the approaches used to treat malignant pleural mesothelioma.

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DWI demonstrates a larger area of infarction and may also be useful in the early detection of infarction. Recent progress in the development of nanoporous graphene based materials has generated enormous potential for water purification technologies. Here, we reconsider the determination of the withdrawal period of milk with data below the limit of quantification. Forty-five patients were diagnosed with fractures of the inferior wall of one orbit. Effects of gamma-secretase cleavage-region mutations on APP processing and Abeta formation: interpretation with sequential cleavage and alpha-helical model. The benzodiazepine receptor agonist beta-carboline ZK 93423 blocked convulsions induced by kainate but had no effect on seizures induced by N-methyl-D-aspartate or quisqualate. In Germany gender-sensitive approaches are part of guidelines for good epidemiological practice as well as health reporting. The hydroalcoholic extract of Cotula cinerea, acetonic extract and gallotanin of Quercus infectoria galls have presented high activity against Bulinus truncatus. Bioinformatics analysis revealed a 50-kb AT-rich region adjacent to the met-8 promoter.

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In acute midbrain slices of mice, we observed that in vitro burst activation of VTA DA neurons potentiated GIRK currents whereas tonic firing depressed these currents. Advances in Poly(4-aminodiphenylaniline) Nanofibers Preparation by Electrospinning Technique. These results indicated that high increase of the L-chain in cases of severe liver disease may be due to either impaired clearance of t-PA in the liver or secondary hyperfibrinolysis accompanied by DIC. Furthermore, the reduced recombination frequency between T and qk may indicate that the proximal gene rearrangement is not a simple inversion. The tooth showed signs of advanced periodontitis and the periodontal pocket was deep, reaching the apex of the palatal root. Literature searching by computer in a university-based drug information center: format of pharmacist-generated input data. Because UDP formed after glucosyl transfer can be directly recycled with sucrose synthase, UDP-glucose formed appears to show high turnover with cellulose synthase in the coupled reaction. This paper proposes a gatekeeping procedure based on the Hommel (1988) test, which offers power advantages compared to other p value-based tests proposed in the literature. Patient 3 underwent interstitial brachytherapy boost for stage IIIA vulvar cancer with vaginal extension. Mood and cognitive functions in anaesthetists working in actively scavenged operating theatres.

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This article summarizes the most currently available data relative to nonvertebral and hip fracture risk reduction for the N-containing bisphosphonates alendronate, ibandronate, risedronate, and zoledronic acid, and presents results of an analysis of comparative efficacy of these compounds using the technique of adjusted indirect comparisons. This study introduces new quality indices, establishes references for AFs and quality indices, and develops a detection method for poor-quality SNP arrays and/or DNA samples. Evaluation of promoter hypermethylation detection in body fluids as elocon generic a screening/diagnosis tool for head and neck squamous cell carcinoma. Justification for additional data analysis: fruit, vegetables, and olive oil and risk of coronary heart disease in Italian women: the EPICOR Study. M(r) and pI isoforms were detected respectively for PtsH and GatB, each being phosphoproteins, as well as RplY which manifested differences with respect to predicted M(r) and pI.

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Neurobehavioral Mechanisms of Traumatic Stress in Post-traumatic Stress Disorder. Biosimilars are of growing clinical, regulatory, and commercial importance. The patient displayed clinical and radiological features similar to multiple sclerosis. Estimation of optimal individual dosage is possible by simple mathematical pharmacokinetic formulas. Maternal medical charts were reviewed for documented discussions regarding delivery room resuscitation. Induction of mesoderm during early amphibian embryogenesis can be mimicked in vitro by adding growth factors, including heparin-binding and type-beta transforming growth factors (TGF-beta), to isolated ectoderm explants from Xenopus laevis embryos. Glutathione disulfide (GSSG), but not reduced glutathione, inhibited the ATP-dependent accumulation of DNP-SG by the vesicles, suggesting that the same, ATP-dependent transport system is responsible for the extrusion of glutathione conjugates and GSSG from liver cells. The tissue obtained was processed histologically as a cell block and examined microscopically.

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Prenatal care comparisons among privately insured, uninsured, and Medicaid-enrolled women. Thus, the combination of triptolide and TRAIL may provide a novel strategy for treating AML by overcoming critical mechanisms of apoptosis resistance. Specially trained researchers observed hissy fits at a clinic over 12 months. Endotracheal continuous positive airway pressure after rescue surfactant therapy. HPLC method for the quantitative determination of sarcophine, a source of cembranoids with cancer chemopreventive activity. Efficacy and safety of aromatase inhibitors in early breast cancer. Monitoring of green waste composting process based on redox potential. Furthermore, Aclar is easily sectioned and does not damage knives used in aldactone 25 mg uses in marathi ultramicrotomy. Thus, syndecan-4 is a critical intrinsic regulator of inflammatory reactions via its effects on OPN function and is a potential novel therapeutic tool for treating inflammatory diseases. Lastly, when venom was exposed to CO in isolation and then placed in plasma, the fibrinogenase was inhibited but the thrombin-like enzyme was not inhibited.

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The follow-up rate was independent of the organisation of the procedures for informing the women about the test results. The average age was 40.7 years old, ranging from 29 to 55 years old. This mechanism involves little dissipation and also explains the formation of nanocorrugations. Fluorescent sensing and discrimination of ATP and ADP based on a unique sandwich assembly of pyrene-adenine-pyrene. These bacteria are opportunistic human pathogens that can cause severe infection in immunocompromised patients, albenza dosing especially those affected by cystic fibrosis (CF), and are often resistant to multiple antibiotics.

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View from the other side: an interview with a pharmacist-surveyor. Aortic thrombosis in the neonate occurs most frequently as a complication of umbilical artery catheterization. We collected data on the diagnosis (ICD10 code), procedure code (NOMESCO), and 9 additional characteristics of patients admitted to the trauma ward of Central Finland Hospital between 2002 and 2008. These pathological changes induced a local infiltration of neutrophils that was quantified as larger in infected animals. First report of gastrocotylinean post-oncomiracidia (Platyhelminthes: Monogenoidea: Heteronchoinea) on gills of flyingfish (Exocoetidae), snapper (Lutjanidae), dolphinfish (Coryphaenidae), and amberjack (Carangidae) from the Gulf of Mexico: decoy hosts and the dilution effect. When the mother was born small, increasing paternal birthweight was associated with increased risk of preterm birth, suggesting that a fetus growing faster than its mother can accommodate might trigger preterm birth. The objectives of this study were to optimize nested polymerase chain reaction (PCR) for Mycobacterium avium complex and Mycobacterium tuberculosis complex and apply them on samples from parrots. Regulation of jun-B gene expression by 1-beta-D-arabinofuranosyl-cytosine in human myeloid leukemia cells. This effect arises from the competition between the magnetic anisotropy and the Zeeman energies for cooling fields perpendicular to the wire axis.

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The extended rehabilitation and prolonged incapacity necessary to recover from immobilization in the plantarflexed position have been avoided. Expression of glutamate receptors on cultured cerebral endothelial cells. This feature can result in poor lesion conspicuity relative to both normal parotid tissue and other parotid abnormalities. Valve interstitial cells are active and aggressive players in aortic valve calcification, but their dynamic mediation of mechanically-induced calcific remodeling is not well understood. Serum alpha-fetoprotein (AFP) was detected by electrochemiluminescence reaction. Although etiologic inferences are limited when using linked-registry data, this hypothesis-generating study may provide new clues to the occupational determinants of specific forms of leukemia. Practical procedure of heparin therapy in recently operated and multi-injured patients. Sequences of internal transcribed spacer rDNA from a subset of specimens support the same species boundaries indicated by CO1 divergence.

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The decrease in PGI2 production correlated with a reduction in the cellular content of immunoreactive prostaglandin H synthase and prostacyclin synthase. HFOV causes earlier FiO(2) reduction and increased PO(2)/FiO(2) ratio compared to PCACV at 8 hr. If so, you might find the management by objectives (MBO) approach to be a very useful management tool. Behaviorally, we find that decade-consistent lures, which share their decade digit with the correct result (e.g. This paper is a continuation of a study begun in 1978 on attitudes toward death.

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Halothane, enflurane, and isoflurane decrease calcium sensitivity and maximal force in detergent-treated rat cardiac fibers. We have developed a retroviral-vector system for the transfer and expression of a cloned blood clotting factor VIII cDNA. We found no evidence that expanding the number of individuals eligible for Medicaid coverage eroded perceived access to care or increased the use of emergency services among adult Medicaid enrollees. This study demonstrated that fusion with an intersomatic cage associated with anterior plating can be used in spine trauma victims, providing an outcome as good as in patients with degenerative disease. This article offers a very different approach to paying primary care physicians that will result in both significantly higher incomes for these underpaid professionals together with incentives for creating a medical home. Interestingly, we found that genes encoding voltage-gated potassium channels and genes related to innate immunity were coordinately up-regulated in subjects who improved with tadalafil treatment compared to those patients who did not. Pulse rate, pre-competition tension and performance in 10,000 meter elite runners of both sexes.

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This is a retrospective analysis of thalamic neuronal and electromyogram activities between subjects with organic dystonia and a subject with psychogenic dystonia in whom a thalamotomy was carried out before the diagnosis of psychogenic dystonia was made. A process that eventually could lead to the development of late diabetic complications. LR is a safe and efficacious treatment for gastric GISTs, providing the advantages of shorter operative time, reduced blood loss, and shorter length of stay, all without compromising post-operative outcomes and survival. OCD rarely occurs in the shoulder joint, where it involves either the humeral head or the atenolol pill identifier glenoid. A self-manufactured pyramid shaped single-grit tool with a small tip radius was used as the scratch tool. Microscopically, the mass was composed of sheets and nests of round to polygonal neoplastic cells with lacy cytoplasm. Although mean percentage changes in I-EMG of UG were not significantly different from ECG, those for VL and VM of IG were different from ECG.

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We used the related articles feature of PubMed and searched reference lists of newly identified trials. Cohort study for monitoring cardiovascular risk factors in children using a primary health care service: methods and initial results. To investigate the in vitro tricor medication dosing antimicrobial susceptibility and the auxotype/serovar distribution of Neisseria gonorrhoeae in Kigali, Rwanda, during 1985-93. In this study, the interference of T-DNA insertion upon Agrobacterium-mediated transformation on the biochemical expression of the host genome is discussed. A sequential study of lesion development at the fold crest indicates that coagulative necrosis occurs on contact and that the vascular defects, hemorrhage and congestion, are secondary to deep corrosion injury. Here, we show that PI3K activity specifically overrides delayed mechanisms effecting permanent G(1) and G(2) phase arrests, but does not affect transient checkpoints arresting cells up to 10 hours after gamma-irradiation.

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