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Adipine (Nifedipine)

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Adipine is used to treat high blood pressure or angina (chest pain). For high blood pressure: Adipine works by relaxing and expanding the blood vessels. This makes the blood flow more easily and lowers blood pressure. Lower blood pressure reduces the strain on your heart. For angina: Adipine works by relaxing and expanding the arteries supplying the heart. This allows more blood and oxygen to reach the heart and decreases the strain on it. Your angina attacks will be less severe and less frequent if there is less strain on the heart.

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Also known as: Nifedipine


Nifedipine is used alone or together with other medicines to treat severe chest pain (angina) or high blood pressure (hypertension). High blood pressure adds to the workload of the heart and arteries. If it continues for a long time, the heart and arteries may not function properly. This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure. High blood pressure may also increase the risk of heart attacks. These problems may be less likely to occur if blood pressure is controlled.

Nifedipine is a calcium channel blocker. It works by affecting the movement of calcium into the cells of the heart and blood vessels. As a result, nifedipine relaxes blood vessels and increases the supply of blood and oxygen to the heart while reducing its workload.

This medicine is available only with your doctor's prescription.


This section provides information on the proper use of a number of products that contain nifedipine. It may not be specific to Adipine PA 10. Please read with care.

In addition to the use of this medicine, treatment for your high blood pressure may include weight control and changes in the types of foods you eat, especially foods high in sodium (salt). Your doctor will tell you which of these are most important for you. You should check with your doctor before changing your diet.

Many patients who have high blood pressure will not notice any signs of the problem. In fact, many may feel normal. It is very important that you take your medicine exactly as directed and that you keep your appointments with your doctor even if you feel well.

Remember that this medicine will not cure your high blood pressure, but it does help control it. You must continue to take it as directed if you expect to lower your blood pressure and keep it down. You may have to take high blood pressure medicine for the rest of your life. If high blood pressure is not treated, it can cause serious problems such as heart failure, blood vessel disease, stroke, or kidney disease.

Swallow the extended release tablet whole. Do not break, crush, or chew it. It is best to take this tablet on an empty stomach.

If you are taking the extended-release tablets, part of the tablet may pass into your stool after your body has absorbed the medicine. This is normal and nothing to worry about.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For treatment of chest pain or high blood pressure: For oral dosage form (capsules): Adults—At first, 10 milligrams (mg) three times a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor. For oral dosage form (extended-release tablets): Adults—At first, 30 or 60 milligrams (mg) once a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 90 mg once a day. Children—Use and dose must be determined by your doctor.


If you overdose Adipine and you don't feel good you should visit your doctor or health care provider immediately.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Detailed Nifedipine dosage information

Side effects

The most common side effects associated with Adipine are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

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Thus, advanced age should not be a limiting factor for performing pelvic lymph node dissection at radical cystectomy. Wear was greater for the larger femoral head and was correlated to capsular distension. Perioperative plasma concentrations of soluble tumour necrosis factor receptor p55 (STNFR p55), interleukin (IL) 1 receptor antagonist (IL-1ra) and IL-6 were measured by immunoassay in 29 consecutive patients undergoing liver resection. This distinction is important because the progression of donor lesions and the development of de novo lesions are independent of each other. Relations between time-and frequency-domain measures of signal transmission from cutaneous afferents to dorsal horn neurons. Noteworthy improvements in the completeness of reporting emerged during this period with a decline from 31.1 percent missing information in 1974 to 6.6 percent missing in 1985. Pasteurized homogenized milk was subdivided and three levels of US Pharmacopeial reference standard penicillin G were added. Ongoing trials (including two Phase III studies) are investigating T-DM1 as single-agent therapy or combined with other chemotherapeutic or biologic agents, and the results should help neurontin 600 mg coupon to define the place of T-DM1 within current treatment algorithms for HER2-positive disease. In this way, inhibition of neurotransmitter release and slow postsynaptic inhibition could be provided by receptor variants derived from the same gene.

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Acculturation, drinking, and alcohol abuse and dependence among Hispanics in the Texas-Mexico border. In infants exposed to CA, insufficient inhibition of high fetal inflammatory cytokine response shortly after birth may increase the risk of BPD. Metaproteomics reveals metabolic transitions between healthy and diseased stony coral Mussismilia braziliensis. Early treatment of gallstone disease in this age group could further improve outcomes. The indirect immunofluorescent antibody test (IFAT) and immunoenzymatic staining technique (IEST) with frozen sections of Brugia malayi and Setaria cervi adult worms as antigens were used to detect IgG levels in rabbits immunized with three different filarial antigens. The results indicated that the Chinese JOACMEQ successfully retained the psychometric properties of the original JOACMEQ and support the usefulness of the Chinese JOACMEQ as an appropriate supplementary diagnostic and outcome measure for Chinese patients suspected of cervical spondylotic myelopathy. THE MONTGOMERY LECTURE, 1917-18: A survey of cases of concomitant squint in the practice of the late Mr. FCM can be injected in 7-8 min or diluted in saline for slower infusion. Insertion mutagenesis of the ferric pyoverdine receptor FpvA of Pseudomonas aeruginosa: identification of permissive sites and a region important for ligand binding. Initial reaction rates for harman disappearance were measured and showed a 4-fold induction by PB and a 10.6-fold induction by MC.

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