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Acupain (Tramadol)

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Acupain is a pain medicine similar to an opioid. It acts in the central nervous system (CNS) to relieve pain. Acupain is used to treat moderate to severe pain in adults. The extended-release form of Acupain is for around-the-clock treatment of pain. This form of Acupain is not for use on an as-needed basis for pain.

Other names for this medication:
Accupain, Bestodol, Contradoc, Contramal, Ivydol, Madol, Midol, Mydol, Neutram, Nomadol, Oshdol, Painex, Paxmax, Ramax, Rimol, Ryzolt, Sayodol, Supridol, Tramacon, Tramafen, Tramakind, Tramest, Trandy, Trapidol, Tridol, Trofel

Similar Products:
Yasmin, Silagra, Medrol, Vermox, Mysoline, Desyrel, Denvar, Rebetol, Zocord, Nedipin, Spinospas, Benzolam, Cardiwell, Cardiloc, Varbend,

Also known as: Tramadol


Acupain (tramadol) is a pain medicine similar to an opioid. It acts in the central nervous system (CNS) to relieve pain.

Acupain is used to treat moderate to severe pain in adults.

The extended-release form of tramadol (Acupain ER) is for around-the-clock treatment of pain. Acupain ER is not for use on an as-needed basis for pain.


Usual Adult Dose for Pain:

Adults (17 years or older): 50 to 100 mg orally every 4 to 6 hours as needed for pain -For patients not requiring rapid onset of analgesic effect: Initial dose: 25 mg orally once a day; titrate in 25 mg increments every 3 days to reach a dose of 25 mg four times a day; thereafter increase by 50 mg as tolerated every 3 days Maximum dose: 400 mg per day.

Usual Adult Dose for Chronic Pain:

Extended-Release (ER): 18 years or older (tramadol-naive): 100 mg orally once a day -Individually titrate in 100 mg increments every 5 days to an effective dose that minimizes adverse reactions -Maximum Dose: 300 mg/day For patients CURRENTLY receiving Immediate-Release (IR) Acupain: Initial Dose: Calculate 24-hour IR requirement and initiate with a total daily ER dose rounded down to the next lowest 100 mg increment orally once a day Conversion from OTHER Opioids: Discontinue all other around the clock opioid drugs prior to initiating therapy -Initial dose: 100 mg ER orally once a day -Individually titrate in 100 mg increments every 5 days to an effective dose that minimizes adverse reactions -Maximum Dose: 300 mg/day.

Usual Geriatric Dose for Pain:

Dose selection should be cautious generally starting at the low end of the dose range Over 75 years: Maximum dose of Immediate-release: 300 mg per day.

Usual Geriatric Dose for Chronic Pain:

Dose selection should be cautious generally starting at the low end of the dose range Over 75 years: Maximum dose of Immediate-release: 300 mg per day.

Usual Pediatric Dose for Pain:

Acupain is not recommended for use in pediatric patients 17 years or older: See Adult Dose.

Detailed Acupain dosage information


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose can be fatal, especially in a child or other person using the medicine without a prescription. Overdose symptoms may include severe drowsiness, pinpoint pupils, slow breathing, or no breathing.

Your doctor may recommend you get naloxone (a medicine to reverse an opioid overdose) and keep it with you at all times. A person caring for you can give the naloxone if you stop breathing or don't wake up. Your caregiver must still get emergency medical help and may need to perform CPR (cardiopulmonary resuscitation) on you while waiting for help to arrive.

Anyone can buy naloxone from a pharmacy or local health department. Make sure any person caring for you knows where you keep naloxone and how to use it.


You may store the suppositories in the refrigerator, but do not freeze them.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Detailed Acupain dosage information

Side effects

The most common side effects associated with Acupain are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Do not drink alcohol. Dangerous side effects or death could occur.

Avoid driving or hazardous activity until you know how Acupain ER will affect you. Dizziness or drowsiness can cause falls, accidents, or severe injuries.

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Multivariate analysis in skull osteometry of the common tree shrew from both sides of the Isthmus of Kra in Southern Thailand. Successful treatment of a case of giant mucocele of the frontal sinus. The bitter taste acuity was significantly poorer in the older sample. Clinical decision models have the potential to improve diagnostic decision-making for these serious conditions. None of these eliminates the sweat- when we take albendazole tablet associated odor (Osmidrosis), which is sometimes present even despite local hygiene and use of deodorants. Engineering modifications for dynamic stereotactically assisted radiotherapy. Posttransplant day significantly influences pharmacokinetics of cyclosporine after hematopoietic stem cell transplantation. Safety and Effectiveness of a Small Incision Lateral Eyebrow Ptosis Repair Technique Using a Frontalis Muscle Transposition Flap.

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