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Actos (Pioglitazone)
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Actos

Actos is a once-daily oral medication for people with type 2 diabetes. Part of the anti-diabetic drug class known as thiazolidinediones. It works by increasing the body’s sensitivity to its own insulin, allowing the hormone to work more effectively at improving blood glucose control.

Other names for this medication:
Adride, Asoformin, Asoride, Bestoglim, Cetapin, Diaglit, Diamet, Diavista, Dimbest, Euroglip, Exerme, Glimestar, Glimiprex, Glyciphase, Glycirest, Ioglime, Metme, Nodiab, Pglit, Pianorm, Pichromet, Pioglar, Pioglitazone, Piokap, Piokare, Piolem, Piolet, Pioli, Piomeri, Pionorm, Pioriv, Piosafe, Piotop, Piozol, Piozone, Tgmet, Triglimiprex, Triglycomet, Triopil, Tripride, Vedapride

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Also known as: Pioglitazone

Description

You should take Actos according to your doctor’s or healthcare provider’s instructions.

Actos comes as a tablet that you swallow.

When to take

You’ll take Actos once a day. Try to take this medication at about the same time each day.

Don’t take more than one dose in a day.

To help make sure that you don’t miss a dose, try setting a reminder on your phone. A medication timer may be useful, too.

Taking Actos with food

You can take Actos tablets with or without food.

Can Actos be crushed, split, or chewed?

No, you shouldn’t break, crush, split, or chew Actos tablets. Broken tablets haven’t been studied, so it’s not known if it’s safe to take a tablet that’s broken.

If you’re having trouble swallowing your Actos tablets, talk with your doctor. They may be able to suggest ways to help you take your medication or recommend other drugs that may be easier for you to take.

Dosage

Usual Adult Dose for Diabetes Type 2:

-Patients without congestive heart failure: Initial dose: 15 mg or 30 mg orally once a day -Patients with congestive heart failure (New York Heart Association [NYHA] Class I or II): Initial dose: 15 mg orally once a day Maintenance dose: 15 mg to 45 mg orally once a day based on glycemic response as determined by HbA1c Maximum dose: 45 mg orally once a day Comments: -This drug exerts its antihyperglycemic effect only in the presence of endogenous insulin and therefore is not expected to be effective in patients with type 1 diabetes mellitus or diabetic ketoacidosis. -Patients concomitantly receiving an insulin secretagogue or insulin may need to reduce the dose of the insulin secretagogue or insulin if hypoglycemia occurs. Use: As an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus in multiple clinical settings

Detailed Actos dosage information

Overdose

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. You may have signs of low blood sugar, such as extreme weakness, blurred vision, sweating, trouble speaking, tremors, stomach pain, confusion, and seizure (convulsions).

Storage

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) and away from excess moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Actos are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Do not take Actos if you are allergic to Actos ingredients. Do not take Actos if you are in a state of diabetic ketoacidosis. Actos is ineffective and possibly harmful in treatment of type 1 diabetes. Do not take Actos if you have congestive heart failure or heart disease, fluid retention, a history of bladder cancer, heart attack, stroke, liver disease, certain eye problems (macular edema), or polycystic ovary syndrome. Actos is not to be used in people with blood in their urine when the cause of this is unknown. Avoid drinking alcohol. It lowers blood sugar level and may interfere with your diabetes treatment. Be careful with Actos if you are pregnant, planning to become pregnant, or breastfeeding. Do not use Actos in treatment of children under 18 years old. Actos may increase the risk of bone fracture in women (usually in the upper arm, hand, or foot). Actos can cause changes in the menstrual cycle (promote ovulation) and increase the risk of becoming pregnant. Do not take Actos for longer than recommended. Taking Actos for more than 1 year may increase your risk of developing bladder cancer.

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