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Actapin (Amlodipine)

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Actapin is a calcium channel blocker medication used to treat high blood pressure and coronary artery disease. While not typically recommended in heart failure, Actapin may be used if other medications are not sufficient for treating high blood pressure or heart-related chest pain.

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Also known as: Amlodipine


Actapin (amlodipine) is a calcium channel blocker that dilates (widens) blood vessels and improves blood flow.

Actapin is used to treat chest pain (angina) and other conditions caused by coronary artery disease.

Actapin is also used to treat high blood pressure (hypertension). Lowering blood pressure may lower your risk of a stroke or heart attack.

Amlodipine is for use in adults and children who are at least 6 years old.


You should take it by mouth. It is better to take Actapin once a day at the same time. Actapin treats angina and hypertension diseases and can be used both by adults and by children. Children of 6-17 years: Starting dosage is 2.5-5 mg. People with vasospastic angina or coronary artery disease: Starting dosage is 5-10 mg. Elderly people, people with hepatic: Starting dosage is 2.5 mg. If you want to achieve most effective results do not stop taking Actapin suddenly.


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include rapid heartbeats, redness or warmth in your arms or legs, or fainting.


Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture, light and heat. Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children in a container that small children cannot open.

Side effects

The most common side effects associated with Actapin are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


You should not take Actapin if you are allergic to amlodipine.

To make sure Actapin is safe for you, tell your doctor if you have ever had:

liver disease; or a heart valve problem called aortic stenosis.

Tell your doctor if you are pregnant or plan to become pregnant. It is not known whether Actapin will harm an unborn baby. However, having high blood pressure during pregnancy may cause complications such as diabetes or eclampsia (dangerously high blood pressure that can lead to medical problems in both mother and baby). The benefit of treating hypertension may outweigh any risks to the baby.

Amlodipine can pass into breast milk, but effects on the nursing baby are not known. Tell your doctor if you are breastfeeding.

Actapin is not approved for use by anyone younger than 6 years old.

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Peptidomic comparison and characterization of the major components of the venom of the giant ant Dinoponera quadriceps collected in four different areas of Brazil. All the isolated saponins were tested for their cytotoxic activities on human caski cervical cancer (Caski) cells, and compounds 13, 17 and 19 exhibited inhibitory effect on Caski cells. In CKD, dietary acid load is associated with serum bicarbonate, suggesting that acidosis may be improved by dietary changes, but not with insulin sensitivity. Physicians who completed the advance directive questionnaire (mean age 68). This review focuses on topological features of three-periodic (framework) p, d, and f metal cyano complexes or cyanometallates, i.e. Use of radioactive gold in the treatment of carcinoma of the bladder: report of 8 cases. Noma (cancrum oris) is a devastating gangrenous disease that leads to severe tissue destruction in the face and is associated with high morbidity and mortality. Namely, when one pathway of intracellular turnover is blocked, it triggers alternative turnover mechanisms, which induce transcription factor proteins that control expression of cytokines and regulators of apoptosis, cell division, differentiation, metabolism, and response to hormones. The emergence of IS76 coincides with the increasing use of tolerant cultivars in the 2000s. The guinea pigs were dermally exposed to nickel (Ni), sodium lauryl sulphate (SLS) and in their combination for 7 and 14 days.

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Implications for this disulfide metabolism of anaerobic hyperthermophiles. The presence of hydroxy fatty acids in sphingomyelins of bovine rennet stomach. Overall, the current evidence suffers from a lack of rigorous study design and compliance with physical activity interventions. A number of thymic preparations are known to stimulate corticotropin (ACTH) release from pituitary cells but it remains unclear whether this effect is mediated by the corticotropin-releasing hormone (CRH) receptor-associated pathway. Connective tissue chambers grew around the silicone tubes implanted under their skin. In an era of dwindling hospital resources and increasing medical costs, safe reduction in postoperative stay has become a major focus to optimize utilization of healthcare resources. Coronary plaque morphology and frequency of ulceration distant from culprit lesions in patients with unstable and stable presentation. Within a certain range of parameters, propagating breathers occur as attractors of the dissipative dynamics.

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Genetic characterization of H5N1 avian influenza viruses isolated in southern China during the 2003-04 avian influenza outbreaks. Therefore, the aim of this study was to investigate the relationship between GERD, gastritis location, HP infection and Cag A positivity. 22 cases with T4 glottic cancer were treated surgically from 1982 to 1998. Cleavage by caspase-3 generates an amino-terminal fragment of gelsolin that can sever actin filaments independently of calcium regulation. Hox proteins functionally cooperate with the GC box-binding protein system through distinct domains. Ultrafast Photoluminescence from the Core and the Shell in CdSe/CdS Dot-in-Rod Heterostructures. Mitochondrial ribosomes synthesize a subset of hydrophobic proteins required for assembly of the oxidative phosphorylation complexes. Prediction of adolescent and adult delinquency from childhood Rorschach ratings. Clinical tests of a new drug combination in the treatment of asthenia, anorexia and dyspeptic syndrome. In vitro/in vivo characterization of a tramadol HCl depot system composed of monoolein and water.

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The Wisconsin personality disorders inventory (WISPI-IV) is a self report instrument for the assessment of DSM-IV personality disorders. Analysis of Clinical and Dosimetric Factors Influencing Radiation-Induced Lung Injury in Patients with Lung Cancer. Evidence is presented for and against both the participation of classic receptors, or proteins closely related to them, as well as for the involvement of yet poorly understood, novel membrane steroid receptors. The environmental contexts of early human occupation of Georgia (Transcaucasia). The pulses are generated from an orthogonal-frequency wave composed of several sinusoidal signals, the amplitudes of which increase with frequency to compensate for higher loss at higher frequency in tissues. Genetic screens by CRISPR/Cas9-mediated genome engineering have become a powerful tool for functional genomics. Three months after the beginning of linear IgA dermatosis, a colic adenocarcinoma was revealed by an acute occlusive syndrome.

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Amifostine protected the middle ear from radiation injury, and we found that the expression of ICAM-1 in the middle ear mucosa was down-regulated. Non-specific BI-RADS IVa/b lesions, such as mastopathic nodules demonstrated rather soft, elastic properties on elastogram (score 1 or 2). If performed by experienced surgeons, this procedure is effective for esophageal reconstruction. Reduction of phosphorylated eIF4E by IGF2BP3 depletion was rescued by EIF4E-BP2 depletion. Tiredness and visual reaction time among nighttime cab drivers: a roadside survey. Multilevel ordinal logistic modelling assessed management by patient and provider factors. The mitotic checkpoint is essential to ensure accurate chromosome segregation by allowing a mitotic delay in response to a spindle defect. The primary outcomes were complete response and time to complete response. Cryopreservation of oocytes from pre-antral follicles has been studied during the past decade.

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Although a familial tendency to develop brain tumors in the absence of well-recognized hereditary disorders is an important issue, it has been rarely reported. Tetrachloroethene (PCE) and trichloroethene (TCE) are ideal solvents for numerous applications, and their widespread use makes them prominent groundwater pollutants. p-HBDNI was considered as a model system and the photophysical properties of other novel 2-amino-3,5-dihydro is elavil a pain medication -4H-imidazol-4-one derivatives were evaluated. Considerable data have been produced in recent years that has benefited a fuller understanding of the processes of steroidogenesis and of cell proliferation at the molecular level. Anticonvulsant therapy, folic acid deficiency, and neuropsychiatric disorders. Low serum HDL cholesterol has a higher prevalence among aymara individuals. Study on extraction process of tannins from Semen Cuscutae and their anti-papilloma activity. At many S6 cysteines, modification by MTSEA caused a decrease in conductance and a favorable change in the free energy of channel opening.

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A randomized trial of vitamin A and vitamin E supplementation for retinitis pigmentosa. We applied repetitive transcranial magnetic stimulation (rTMS) in order to induce interference on visuo-spatial perception in 11 healthy subjects. To correlate the preoperative findings, perforation rate and the mortality vasotec iv dose rate after appendicectomy in the elderly age. However, by replacing the hydrophobic core of the signal peptide with a homopolymeric series of leucines, not only was transport restored but precursor processing was more efficient than for the wild type and was insensitive to disruption of the protonmotive force. Flow-rate had no significant first-order effect on the recovery, but interaction effects with flow-rate were found to be significant.

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Based on the likelihood of transfecting large numbers of local antigen-presenting cells, a Phase I study in patients with Stage IV melanoma was conducted to determine the practicality, toxicity of, and immune responses to repeated infusions into a groin lymph node of escalating doses of a DNA plasmid encoding tyrosinase epitopes. Accurate performance requires precise coordination between the shoulder and elbow joints during movement reversals. Furthermore, other factors, such as contraction of the skin graft, use of the remnant ear cartilage in construction of the tragus, and the number of surgeries required, all affect the final results of total auricular reconstruction for microtia, especially with reference to the contour of the constructed ear, morphologic locations of the auricular features, contraction, circulatory dysfunction, resorption, etc. Inclusion of HIF resulted in a moderate increase of the absorptive transport, as well as a significant concentration dependent decrease of the secretory transport, without compromising the integrity of the monolayer. Clinical study of the antihypertensive effects of debrisoquin sulfate in combination with hydrochlorothiazide. A MEDLINE search (1966-December 2002) was performed using SCH 48461, SCH 58235, ezetimibe, and 2-azetidinone as key words. Air ionization inside the filaments also opens promising perspectives for laser-induced condensation and lightning control. Lifestyle changes glucophage pill are advocated for individuals not achieving these targets. The effect of tolbutamide on cerebral blood flow during hypoxia and hypercapnia in the anaesthetized rat. This is the first report on the generation of squamous cell lines of FA patients.

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Tubal reconstructive surgery and assisted reproductive techniques must be considered complementary forms of treatment for women with tubal factor infertility, and training in tubal reconstructive surgery should be an integral part of subspecialty training in reproductive endocrinology and infertility. Experimental studies on the physiopathology of neurogenic bladder due to spinal cord injury, with special reference to the effect of drugs on the smooth muscle of the bladder in the acute stage. Interaction of Ni(II) and Cu(II) with a metal binding sequence of histone H4: AKRHRK, a model of the H4 tail. During apoptosis, lamin proteins are degraded by caspase 6 and the contribution made by phosphorylation has not been proven. Effect of androgenic hormone combined with hydroxyurea (NSC-32065) on hematopoietic system of patients with cancer. To determine the relationship between a single point mutation in RET proto-oncogene and the occurrence of multiple endocrine neoplasia type 2B (MEN-2B) in a Chinese pedigree. Inhibition cymbalta drug side effects of cholate synthesis might be accounted for by repressed production of deoxycholic and cholic acid from cholesterol as well as by repressed conjugation of cholic acid with taurine and glycine. Using the principles of the Belmont Report as its framework, this paper draws on developmental theories to discuss ethical issues specific to the conduct of research with adolescents. The objective was in vivo screening of four phytochemicals/extracts and a fungal immunomodulatory protein (FIP) against an Eimeria acervulina infection in broilers. Successful recordings of single and multiunit activity with parallel depth profiles of spontaneous and evoked field potentials are shown.

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