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Acepril (Enalapril)
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Acepril

Acepril is an ACE inhibitor medication used to treat high blood pressure, diabetic kidney disease, and heart failure. For heart failure, it is generally used with a diuretic, such as furosemide. It is given by mouth or by injection into a vein.

Other names for this medication:
Auspril, Bajaten, Bidinatec, Calnate, Cetampril, Converten, Dabonal, Defluin, Ditensor, Ekaril, Enacor, Enalagamma, Enaldun, Enaprotec, Envas, Hipertan, Imotoran, Intonis, Invoril, Myoace, Naprilene, Neotensin, Norpril, Ofnifenil, Presopril, Presuren, Renapril, Tenaten, Tencas, Vimapril

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Also known as: Enalapril

Description

Acepril (enalapril) is an ACE inhibitor. ACE stands for angiotensin converting enzyme.

Acepril is used to treat high blood pressure (hypertension) in adults and children who are at least 1 month old.

Acepril is also used to treat congestive heart failure in adults.

Acepril is also used to treat a disorder of the ventricles (the lower chambers of the heart that allow blood to flow out of the heart). This disorder can decrease the heart's ability to pump blood to the body.

Dosage

Usual Adult Dose for Hypertension:

Initial dose: 5 mg orally once a day Maintenance dose: 10 to 40 mg orally per day as a single dose or in 2 divided doses Maximum dose: 40 mg orally daily as a single dose or in 2 divided doses In combination with diuretics: Initial dose: 2.5 mg orally once a day If feasible, the diuretic should be discontinued 2 to 3 days prior to initiation of therapy with enalapril. If required, diuretic therapy may be gradually resumed.

Usual Adult Dose for Congestive Heart Failure:

Initial dose: 2.5 mg orally once a day Maintenance dose: 2.5 to 20 mg daily in 2 divided doses Maximum dose: 40 mg orally per day in 2 divided doses Comments: -Treatment is usually combined with diuretics and digitalis. -Doses should be titrated upward, as tolerated, over a period of a few days or weeks.

Usual Adult Dose for Left Ventricular Dysfunction:

Initial dose: 2.5 mg orally twice a day Maintenance dose: 20 mg orally per day in 2 divided doses Comments: -After the initial dose, the patient should be observed for at least 2 hours and until blood pressure has stabilized for at least an additional hour. -If possible, the dose of any concomitant diuretic should be reduced which may diminish the likelihood of hypotension.

Usual Pediatric Dose for Hypertension:

Children 1 month to 17 years: Initial dose: 0.08 mg/kg/day (up to 5 mg) in 1 to 2 divided doses. Adjust dosage based on patient response. Maximum dose: Doses greater than 0.58 mg/kg (40 mg) have not been evaluated in pediatric patients. Comment: -Not recommended in neonates and in pediatric patients with glomerular filtration rate less than 30 mL/min, as no data are available.

Detailed Acepril dosage information

Overdose

If you overdose Acepril and you don't feel good you should visit your doctor or health care provider immediately. Symptoms of Acepril overdosage: fainting, dizziness.

Storage

Store at room temperature below 30 degrees C (86 degrees F) away from moisture and heat. Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Acepril are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

You should not use Acepril if you are allergic to enalapril:

you have hereditary angioedema; you recently took a heart medicine called sacubitril; or you have ever had a severe allergic reaction to any ACE inhibitor (benazepril, captopril, fosinopril, lisinopril, moexipril, perindopril, quinapril, ramipril, or trandolapril).

Do not take Acepril within 36 hours before or after taking medicine that contains sacubitril (such as Entresto).

If you have diabetes, do not use enalapril together with any medication that contains aliskiren (a blood pressure medicine).

You may also need to avoid taking enalapril with aliskiren if you have kidney disease.

To make sure this medicine is safe for you, tell your doctor if you have:

kidney disease (or if you are on dialysis); liver disease; or an electrolyte imbalance (such as high levels of potassium in your blood).

Do not use if you are pregnant. If you become pregnant, stop taking this medicine and tell your doctor right away. Enalapril can cause injury or death to the unborn baby if you take the medicine during your second or third trimester.

You should not breast-feed while you are using Acepril.

Enalapril is not approved for use by anyone younger than 1 month old.

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HIV protease inhibitors (PIs) acutely and reversibly inhibit the insulin-responsive glucose transporter Glut 4, leading to peripheral insulin resistance and impaired glucose tolerance. Flame atomic absorption spectrophotometric methods were developed for the determination of zinc, copper, arsenic, iron and selenium in blood samples. These results suggest that PM effect in this in vitro model of opiate withdrawal may be due to extracellular type II PLA(2) inhibition. In this paper, we describe the direct patterning of protein by microcontact printing. Allergy to plant-derived foods is associated with birch pollinosis in central and northern Europe. The spontaneous bundle oscillations allowed us to characterize several properties of mechano-electrical transduction without artificial loading the hair bundle with a mechanical stimulus probe.

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Postnatal gene transfer in respiratory epithelium has been inefficient, particularly in submucosal gland cells, the target cells for cystic fibrosis transmembrane regulator (CFTR) gene transfer in cystic fibrosis. EXPERIENCE IN THE REIMPLANTATION OF THE QUADRILATERAL CARTILAGE REMOVED BY SUBMUCOSAL RESECTION FROM THE NASAL SEPTUM. Xenogeneic dopaminergic grafts reverse behavioral deficits induced by 6-OHDA in rodents: effect of 15-deoxyspergualin treatment. The drug has a half-life of more than 4 hours and thus can be administered in a twice daily schedule. We found a significant association between endometrial cancer risk and XRCC1 polymorphisms and haplotype TG in postmenopausal Japanese women. To observe how acupuncture stimulation influences the visceral nociception in rat and to clarify the interactions between acupuncture or somatic input and visceral nociceptive inputs in the spinal dorsal horn. Among mammals, experimental evidence indicates that females attract mating partners by using olfactory and visual signals to advertise their reproductive state. Buparlisib is a potent and highly specific oral pan-class I PI3K inhibitor, which is currently under investigation in patients with breast cancer.

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Chemical approaches to triggerable lipid vesicles for drug and gene delivery. How the clergyman can assist the physician in the care of a patient. At term, no significant reduction in SAD-induced CP was seen as a result of AA treatment. This might contribute to the increased cardiovascular morbidity in hypopituitary patients. Effect of molybdate on methanogenic and sulfidogenic activity of biomass. solieri differentiated during the last glaciation events before recolonizing the actual range of the species. A localized stripe solution to a reaction-diffusion equation can lose stability simultaneously to zigzag and varicose perturbations at a codimension-two point. These findings suggest that some murine spleen cells have receptors to a structure on autologous red blood cells, which is recognized by an anti-Aspergillus niger glucose oxidase monoclonal antibody. For the aminoglycoside antibiotics, the hypersensitive period in rats occurs during the second and third postnatal weeks.

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